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sp1 sp3 inhibitor mithramycin  (Tocris)


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    Structured Review

    Tocris sp1 sp3 inhibitor mithramycin
    Sp1 Sp3 Inhibitor Mithramycin, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 18 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sp1+sp3+inhibitor+mithramycin/SUN-B+8155/pmc03425823-43-161-166
    Average 93 stars, based on 18 article reviews
    sp1 sp3 inhibitor mithramycin - by Bioz Stars, 2026-10
    93/100 stars

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    other:

    Article Title: Prostaglandin E 2 increases fibroblast gene-specific and global DNA methylation via increased DNA methyltransferase expression
    Article Snippet: Cells were plated unless otherwise noted at 5 × 10 5 cells/well in 6-well plates, serum starved overnight, and treated with the following reagents: PGE 2 (10 −9 to 10 −6 M), the prostacyclin [prostaglandin I 2 (PGI 2 )] analogs iloprost (1 μM) and treprostinil (1 μM), PGD 2 (1 μM), the thromboxane A 2 analog U-4419 (1 μM), and the EP2 agonist butaprost free acid (500 nM) (all from Cayman Chemical, Ann Arbor, MI, USA); aspirin (200 μM), the DNA-damaging agent temozolomide (100 and 250 μM), and actinomycin D (2.5 μg/ml) (all from Sigma-Aldrich, St. Louis, MO, USA); IL-1β (10 ng/ml; BD Biosciences, Sparks, MD, USA); the EP3 agonist ONO-AE3-248 (100 nM), the EP4 agonist ONO-AE1-329 (100 nM), and the EP4 antagonist ONO-AE3-208 (100 nM) (kind gifts from Ono Pharmaceuticals, Osaka, Japan); the adenyl cyclase activator forskolin (100 μM; EMD Chemicals, San Diego, CA, USA); the EP2 antagonist AH6809 (10 μM; Enzo Life Sciences, Farmingdale, NY, USA); and the Sp1/Sp3 inhibitor mithramycin (25–50 nM; Tocris Bioscience, Bristol, UK).



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    93
    Tocris sp1 sp3 inhibitor mithramycin
    Sp1 Sp3 Inhibitor Mithramycin, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sp1+sp3+inhibitor+mithramycin/SUN-B+8155/pmc03425823-43-161-166
    Average 93 stars, based on 1 article reviews
    sp1 sp3 inhibitor mithramycin - by Bioz Stars, 2026-10
    93/100 stars
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